Is it worth using IM SQL Tuning to fine tune a SQL that all relevant tables are already in in-memory?

Yes, it is still worth it to tune your SQL with IM SQL Tuning even all the tables are already in in-memory. Our IM SQL Tuning will check whether there are any tables are not necessary to put into in-memory to save your in-memory space. For certain situations; in-memory objects may deteriorate query plan by using unnecessary in-memory full table scan operations. IM SQL Tuning makes recommendations to reverse certain in-memory full table scans by SQL hints application.